Achieving Thrombus Reduction With Hydromer® Medical Device Coatings

inSep 04, 2019

Thrombogenicity: A Term No One Wants To Hear

What is Thrombogenicity? It is the tendency of a material, foreign to the human body, that comes in contact with blood producing a thrombus, or clot. It not only refers to fixed thrombi, but also to emboli, which are thrombi that have become detached and travel through the bloodstream.

Why doesn’t anyone want to hear it? The reason is because this can be extremely dangerous to patients that have had implants, catheters or other devices inserted without a thromboresistant coating. In addition to impairing functionality of the medical device, fibrin production and clot formation can lead to limited or blocked blood flow. They can also cause a buildup of blood clots that are able to travel to the arteries or veins in the brain, heart, kidneys, lungs and limbs, which in turn can cause implants to be rejected by the body, heart attack, stroke, damage to the body’s organs or even death.

Minimizing Medical Device Induced Thrombosis

– Hydromer’s thromboresistant hydrophilic coatings are specifically designed to cause minimal activation and significant reduction in platelet adhesion to medical device surfaces.
– Hydromer’s highly robust thromboresistant coatings, have been developed to withstand varying blood/fluid flow conditions and many mechanical challenges resulting in reduced thrombus accumulation.

In a recent independent study, Hydromer’s thromboresistant coatings were shown to prevent the adherence of 111 IN-labeled platelets. These catheters also showed little, if any, adherence of blood clots. Download to learn more about the results of our 3rd party study!

In an article by RSC Publishing in their “Analytical Methods” publication, the two Hydromer thromboresistant coatings outperformed all the other coatings tested. Read the entire article here.